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veins, where the backward pressure is so great that the blood flows down again, and so a vicious circle is established. The blood therefore loses more and more of its oxygen, and so fails to nourish the tissues.

The ulcer of the leg associated with varicose veins has already been described.

Hæmorrhage may take place from a varicose vein as a result of a wound or of ulceration of its wall. Increased intra-venous pressure produced by severe muscular strain may determine rupture of a vein exposed in the floor of an ulcer. If the limb is dependent, the incompetency of the valves permits of rapid and copious bleeding, which may prove fatal, particularly if the patient is intoxicated when the rupture takes place and no means are taken to arrest the hæmorrhage. The bleeding may be arrested at once by elevating the limb, or by applying pressure directly over the bleeding point.

Phlebitis and thrombosis are common sequelæ of varix, and may prove dangerous, either by spreading into the large venous trunks or by giving rise to emboli. The larger the varix the greater is the tendency for a thrombus to spread upwards and to involve the deep veins. Thrombi usually originate in venous cysts or pouches, and at acute bends on the vessel, especially when these are situated in the vicinity of the knee, and are subjected to repeated injuries—for example in riding. Phleboliths sometimes form in such pouches, and may be recognised in a radiogram. In a certain proportion of cases, especially in elderly people, the occurrence of thrombosis leads to cure of the condition by the thrombus becoming organised and obliterating the vein.

Treatment.—At best the treatment of varicose veins is only palliative, as it is obviously impossible to restore to the vessels their normal structure. The patient must avoid wearing anything, such as a garter, which constricts the limb, and any obvious cause of direct pressure on the pelvic veins, such as a tumour, persistent constipation, or an ill-fitting truss, should be removed. Cardiac, renal, or pulmonary causes of venous congestion must also be treated, and the functions of the liver regulated. Severe forms of muscular exertion and prolonged standing or walking are to be avoided, and the patient may with benefit rest the limb in an elevated position for a few hours each day. To support the distended vessels, a closely woven silk or worsted stocking, or a light and porous form of elastic bandage, applied as a puttee, should be worn. These appliances should be put on before the patient leaves his bed in the morning, and should only be removed after he lies down at night. In this way the vessels are never allowed to become dilated. Elastic stockings, and bandages made entirely of india-rubber, are to be avoided. In early and mild cases these measures are usually sufficient to relieve the patient's discomfort.

Operative Treatment.—In aggravated cases, when the patient is suffering pain, when his occupation is interfered with by repeated attacks of phlebitis, or when there are large pouches on the veins, operative treatment is called for. The younger the patient the clearer is the indication to operate. It may be necessary to operate to enable a patient to enter one of the public services, even although no symptoms are present. The presence of an ulcer does not contra-indicate operation; the ulcer should be excised, and the raw surface covered with skin grafts, before dealing with the veins.

The operation of Trendelenburg is especially appropriate to cases in which the trunk of the great saphena vein in the thigh is alone involved. It consists in exposing three or four inches of the vein in its upper part, applying a ligature at the upper and lower ends of the exposed portion, and, after tying all tributary branches, resecting this portion of the vein.

The procedure of C. H. Mayo is adapted to cases in which it is desirable to remove longer segments of the veins. It consists in the employment of special instruments known as “ring-enucleators” or “vein-strippers,” by means of which long portions of the vein are removed through comparatively small incisions.

An alternative procedure consists in avulsing segments of the vein by means of Babcock's stylet, which consists of a flexible steel rod, 30 inches in length, with acorn-shaped terminals. The instrument is passed along the lumen of the segment to be dealt with, and a ligature applied around the vein above the bulbous end of the stylet enables nearly the whole length of the great saphena vein to be dragged out in one piece. These methods are not suitable when the veins are brittle, when there are pouches or calcareous deposits in their walls, or where there has been periphlebitis binding the coils together.

Mitchell of Belfast advises exposing the varices at numerous points by half-inch incisions, and, after clamping the vein between two pairs of forceps, cutting it across and twisting out the segments of the vein between adjacent incisions. The edges of the incisions are sutured; and the limb is firmly bandaged from below upwards, and kept in an elevated position. We have employed this method with satisfactory results.

The treatment of the complications of varix has already been considered.

Angioma[4]

[4] In the description of angiomas we have followed the teaching of the late John Duncan.

Tumours of blood vessels may be divided, according to the nature of the vessels of which they are composed, into the capillary, the venous, and the arterial angiomas.

Capillary Angioma

The most common form of capillary angioma is the nævus or congenital telangiectasis.

Nævus.—A nævus is a collection of dilated capillaries, the afferent arterioles and the efferent venules of which often share in the dilatation. Little is known regarding the etiology of nævi beyond the fact that they are of congenital origin. They often escape notice until the child is some days old, but attention is usually drawn to them within a fortnight of birth. For practical purposes the most useful classification of nævi is into the cutaneous, the subcutaneous, and the mixed forms.

The cutaneous nævus, “mother's mark,” or “port-wine stain,” consists of an aggregation of dilated capillaries in the substance of the skin. On stretching the skin the vessels can be seen to form a fine network, or to run in leashes parallel to one another. A dilated arteriole or a vein winding about among the capillaries may sometimes be detected. These nævi occur on any part of the body, but they are most frequently met with on the face. They may be multiple, and vary greatly in size, some being no bigger than a pin-head, while others cover large areas of the body. In colour they present every tint from purple to brilliant red; in the majority there is a considerable dash of blue, especially in cold weather.

Unlike the other forms of nævi, the cutaneous variety shows little tendency to disappear, and it is especially persistent when associated with overgrowth of the epidermis and of the hairs—nævoid mole.

The treatment of the cutaneous nævus is unsatisfactory, owing to the difficulty of removing the nævus without leaving a scar which is even more disfiguring. Very small nævi may be destroyed by a fine pointed Paquelin thermo-cautery, or by escharotics, such as nitric acid. For larger nævi, radium and solidified carbon dioxide (“CO2 snow”) may be used. The extensive port-wine stains so often met with on the face are best left alone.

The subcutaneous nævus is comparatively rare. It constitutes a well-defined, localised tumour, which may possess a distinct capsule, especially when it has ceased to grow or is retrogressing. On section, it presents the appearance of a finely reticulated sponge.

Although it may be noticed at, or within a few days of, birth, a subcutaneous nævus is often overlooked, especially when on a covered part of the body, and may not be discovered till the patient is some years old. It forms a rounded, lobulated swelling, seldom of large size and yielding a sensation like that of a sponge; the skin over it is normal, or may exhibit a bluish tinge, especially in cold weather. In some cases the tumour is diminished by pressing the blood out of it, but slowly fills again when the pressure is relaxed, and it swells up when the child struggles or cries. From a cold abscess it is diagnosed by the history and progress of the swelling and by the absence of fluctuation. When situated over one of the hernial openings, it closely simulates a hernia; and when it occurs in the middle line of the face, head, or back, it may be mistaken for such other congenital conditions as meningocele or spina bifida. When other means fail, the use of an exploring needle clears up the diagnosis.

Mixed Nævus.—As its name indicates, the mixed nævus partakes of the characters of the other two varieties; that is, it is a subcutaneous nævus with involvement of the skin.

It is frequently met with on the face and head, but may occur on any part of the body. It also affects parts covered by mucous membrane, such as the cheek, tongue, and soft palate. The swelling is rounded or lobulated, and projects beyond the level of its surroundings. Sometimes the skin is invaded by the nævoid tissue over the whole extent of the tumour, sometimes only over a limited area. Frequently the margin only is of a bright-red colour, while the skin in the centre resembles a cicatrix. The swelling is reduced by steady pressure, and increases in size and becomes tense when the child cries.

Fig. 68.—Mixed Nævus of Nose which was subsequently cured by Electrolysis.

Fig. 68.—Mixed Nævus of Nose which was subsequently cured by Electrolysis.

Prognosis.—The rate of growth of the subcutaneous and mixed forms of nævi varies greatly. They sometimes increase rapidly, especially during the first few months of life; after this they usually grow at the same rate as the child, or more slowly. There is a decided tendency to disappearance of these varieties, fully 50 per cent. undergoing natural cure by a process of obliteration, similar to the obliteration of vessels in cicatricial tissue. This usually begins about the period of the first dentition, sometimes at the second dentition, and sometimes at puberty. On the other hand, an increased activity of growth may be shown at these periods. The onset of natural cure is recognised by the tumour becoming firmer and less compressible, and, in the mixed variety, by the colour becoming less bright. Injury, infection, or ulceration of the overlying skin may initiate the curative process.

Towards adult life the spaces in a subcutaneous nævus may become greatly enlarged, leading to the formation of a cavernous angioma.

Treatment.—In view of the frequency with which subcutaneous and mixed nævi disappear spontaneously, interference is only called for when the growth of the tumour is out of proportion to that of the child, or when, from its situation—for example in the vicinity of the eye—any marked increase in its size would render it less amenable to treatment.

The methods of treatment most generally applicable are the use of radium and carbon dioxide snow, igni-puncture, electrolysis, and excision.

For nævi situated on exposed parts, where it is desirable to avoid a scar, the use of radium is to be preferred. The tube of radium is applied at intervals to different parts of the nævus, the duration and frequency of the applications varying with the strength of the emanations and the reaction produced. The object aimed at is to induce obliteration of the nævoid tissue by cicatricial contraction without destroying the overlying skin. Carbon-dioxide snow may be employed in the same manner, but the results are inferior to those obtained by radium.

Igni-puncture consists in making a number of punctures at different parts of the nævus with a fine-pointed thermo-cautery, with the object of starting at each point a process of cicatrisation which extends throughout the nævoid tissue and so

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